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Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Design and implement in vitro screening to identify lead therapeutic biologics and address mechanisms-of-action. Perform complex cell-based functional experiments independently. Act as a subject matter expert (SME) for drug discovery in the GI & Inflammation/Neuroscience (GI^2/NS) therapeutic areas.

How you will contribute:

Provide broad assay development support for early stage drug discovery projects in GI & Inflammation, and Neuroscience (GI^2 and NS) therapeutic areas
Design, troubleshoot, validate, and execute a variety of assays to characterize developability and mechanism of action of novel biologics
Collaborate with automation engineers to leverage automated/semi-automated execution of cell based assays
Analyze and interpret data, interface with project teams to meet timelines and milestones, and present findings
Spend ~85% of time in laboratory to maintain and implement cell based assay platform and perform experiments

DIMENSIONS AND ASPECTS

Experienced in the design, development and implementation of in vitro cell based functional assays to study target-specific drug effects
Knowledge and experienced in cell biology and antibody characterization
Experience with cell culture and functional assays including: on-cell binding, reporter assays, PSR, MSD, flow cytometry, cell adhesion, cell migration, and imaging
Skilled in data analysis, interpretation, and data reporting
Experience in troubleshooting, assay optimization and data quality control is a plus
Experience with functional characterization of CART is a plus
Working knowledge of disease areas in GI/Inflammatory, Neuroscience and/or immunology is a plus

Leadership

Excellent written and verbal communication skills, along with the ability to work with cross-functional project teams

Ability to work independently and self-driven in managing and accomplishing daily tasks

Decision-making and Autonomy

Design and iterate complex protocols for cell-based functional assay development
Independently manages workflow based on high-level direction
Troubleshoots complex problems and participates in innovation and/or optimization of established processes to ensure data relevance and quality
Analyze and summarize results to impact data-driven decision making

Interaction

Ability to work both independently and in a matrix-environment
Works well under minimal supervision
Collaborative and team-oriented
Engage within and outside of the department to understand cross-functional priorities

Innovation

Participates in new technology assessment under supervision

Minimum Requirements/Qualifications:

MS with 2+ years experience, or
BS with 3+ years experience

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$84,000.00 - $132,000.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

YesIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Learn more about this Employer on their Career Site

Research Senior Associate, Biologics In Vitro Pharmacology (GI/Inflammation and Neuroscience)